Cancer, ever evolving

  • Maley and his research team apply evolutionary and ecological theory to three problems in cancer:

  • Neoplastic Progression

    We developing methods to measure the evolutionary dynamics among cells of a tumor that drive progression from normal tissue to malignant cancers, and methods to prevent cancer based on slowing that evolution.

    Therapeutic Resistance

    We are developing evolutionary approaches to prevent the evolution of resistance to cancer therapies.

    Peto's Paradox

    We are discovering how large, long-lived animals such as elephants and whales suppress cancer better than humans (a problem called Peto's Paradox).