The Maley Lab is made up of microbiologists, computer scientists, evolutionary biologists, artists, research technologists, and geneticists. We explore the evolution of cancer using a variety of tools, techniques, and transdisciplinary ways of thinking.
Carlo Maley, PhD
Prof. Maley is a cancer biologist, evolutionary biologist and computational biologist, working at the intersection of those fields. His lab uses genomic data mining, phylogenetics, computational modeling, as well as wet-lab techniques to develop better methods to prevent cancer and improve cancer management. For more information, please visit Dr. Maley's profile here.
Angelo Fortunato, PhD
Assistant Research Professor
Dr. Angelo Fortunato’s research focuses on cancer evolution, cancer biology, evolutionary biology and molecular genetics. He is working on human cancer and development of novel model organisms in cancer. He received his Ph.D. in Ecology and Evolutionary Biology from Rice University, Houston, Texas, and a second Ph.D. in Experimental and Clinical Oncology, from University of Florence, Italy. Read more about Dr. Fortunato and his work here.
Diego Mallo, PhD
Postdoctoral Research Associate
Diego Mallo is a biologist and computational phylogeneticist aspiring to understand the evolution of somatic cells. He develops computational methods that use genomic information to reconstruct the past; specifically, how cancers initiate and evolve within a patient. He thinks that understanding the mechanisms and dynamics of this process are not only discoveries by themselves but will also change how cancer is prevented and managed in the clinic. He has also worked on evolutionary modeling and species tree reconstruction methods and is a firm supporter of open source and data. In his free time, you may find him backpacking in a national park, cycling, or skiing.
To learn more about Dr. Mallo's work, click here.
Postdoctoral Research Associate
After completing a Masters & Ph.D. at Oxford on social evolution, the major evolutionary transitions in individuality, and specifically the evolution of multicellularity, Dr. Kapsetaki was enthused by the idea of looking at cancer from an evolutionary perspective. That is, as a selfish element in a cooperative cellular society, the multicellular organism. As a Postdoctoral Research Fellow, Dr. Kapsetaki will be using this perspective to tackle several questions, including connections between fusion, chimerism, and the evolution of transmissible cancers. She will also be using placozoa as an experimental model system.
In her spare time, Dr. Kapsetaki will be performing at concert venues as a pianist and will be exploring art, poetry, composition, songwriting, and photography.
To learn more about Dr. Kapsetaki, visit her webpage here.
Assistant Research Technologist
Shrinath is a research volunteer in the lab. He has an undergraduate degree (B.Tech) in Biotechnology from Anna University. He received a master degree in Cell and Molecular Biology from the University of Texas at Dallas. He has been trained as a molecular biologist. During his masters, he worked with Dr.Nikki Delk on examining the effects of cytokines in breast cancer cells with respect to its receptor status. Since then, he has started to develop a strong interest in the evolutionary perspectives of cancer development and multicellularity. Currently, he is working with Dr. Maley on developing a model to assess therapeutic resistance in cancer.
Valerie's work focuses in on comparative oncology, which aims to compare the rates, incidence and etiology of cancers across animals and throughout the Tree of Life. She is primarily interested in studying the incidence of cancer in wild-caught flighted animals: bats and birds. In addition to gaining valuable insights into the incidence of cancer in wild, natural populations of animals, she hopes that her work can be translated into a One-Health perspective, a concept that closely ties the health of wild animals and humans to the ecosystems that we share. She received her Bachelor's of Science in Biology in 2014 from Arizona State University and is currently pursuing a Ph.D. in Biological Design.
Zach received his undergraduate degree in Genetics, Cell, and Developmental Biology and I is currently pursuing his doctorate in Evolutionary Biology. Zach is interested in all of the intersections that evolutionary theory makes with cancer biology, with a particular focus on the comparative oncology projects. He currently studies the incidence and etiology of cancers in the large Felines.
Scientific Research Curator
Pamela Winfrey specializes in art/science exhibitions, programs, residencies, and artworks. She has been the lead curator in emerging art forms for Creative Capital, represented the United States on the interactive arts panel at Ars Electronica in Linz, and worked for many years at the Exploratorium in San Francisco. She just finished a book on Marconi and is beginning a book about Palladio. She is also a playwright and screenwriter. Learn more about her work by visiting her website here.